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Only around 0.1% of endogenous oxalate arises from glycine catabolism, whereas approximately 15% of the daily endogenous production of glyoxylate derives from 4-hydroxyproline

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Additionally, analogs of the peptide have been shown to decrease infarct size in ischemia-reperfusion injuries and strengthen antioxidant defenses, highlighting their potential to protect brain health and support recovery from neurological damage (7)

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In addition, metabolic disease and systemic inflammation are tightly intertwined, and metabolic problems like uncontrolled diabetes are risk factors for Alzheimers